The Biotechnology Centre (UG) & The Institute for Genomic Diversity (Cornell University)

Training Course on the Use of Molecular Markers for

Characterization of Genetic Resources

30 June – 11 July 2008

Agenda

 

 

 

 

Lectures, Seminars, & Laboratories

Location, Lead person

30 June Monday

09:00

Welcoming Remarks

Sam Offei

 

 

 

Group introductions

T Fulton

 

10:30

Break

 

 

10:45

Schedule, materials, expectations

Introduction

Plant Genetic Diversity & evaluation

About genetic markers, importance of

Properties of markers, choosing of

DNA basics, restriction enzymes & DNA-based markers

T Fulton

 

12:00

Lunch

 

 

01:30

Lab Safety, Use of equipment

DNA grinding and CTAB extraction

DNA extraction w/FTA paper system

 

Team

 

 

??

Cocktail reception

 

 

 

 

 

1 July

09:00

Make DNA quantification agarose gel

Team

Tuesday

09:30

The Polymerase Chain Reaction & PCR-based markers

PCR techniques with arbitrary primers

Sequence-tagged site markers: Microsatellites, CAPS, others

T Fulton

 

10:30

Break

 

 

11:00

Load & start quantification gel

Team

 

12:00

Lunch

 

 

01:30

Demo of horizontal PAGE and about KT

Ed Southern

 

02:30

Break

 

 

03:00

Applying MAS in cocoa breeding and other research in Ghana: challenges and role of the Mobile Laboratory

Jemmy Takrama

 

04:00

Stain gel, check DNA, quantify

Discussion

Team

S Mitchell, T Fulton

 

 

 

 

2 July Wed

09:00

PCR with SSRs

Prepare gel

Team

 

10:30

Break

 

 

11:00

AFLP markers

S Mitchell

 

 

12:30

Lunch

 

 

01:30

Genetic mapping

R Koebner

 

03:00

Break

 

 

03:30

Load gel

Question and Answer session

 

 

 

 

 

3 July Thursday

09:00

Stain gel, take picture

Team

 

09:30

Genetic Diversity & use of markers

S Mitchell

 

10:30

Break

 

 

11:00

Analyzing SSR results

S Mitchell

 

12:00

Lunch

 

 

01:30

Use of databases: Sequence Retrieval etc

Primer design

Web Resources

Computer Lab

T Fulton

 

 

Break where convenient

 

 

 

Literature Team assignments (flexible)

T Fulton

 

 

 

 

4 July Friday

09:00

New technologies: DNA sequencing, ESTs, SNPs, Comparisons of markers, Considerations in choosing, Cost-saving strategies

T Fulton

 

10:30

Break

 

 

11:00

Proposal Writing

T Fulton

 

12:00

Lunch

 

 

01:30

Marker-assisted selection: Principles and applications

R Koebner

 

03:00

Break

 

 

03:30

QTL identification & use in industry: case study in tomato

T Fulton

 

04:30

Problems, questions, discussion
1st week wrap-up

 

 

 

 

 

5 July

Saturday

 

Field trip to Cape Coast/Elimina Castles/Canopy Walk?

 

 

6 July

Sunday

 

Free time

 

 

 

7 July

Monday

09:00

Phenotyping: Methods, experimental design & statistical analyses used in breeding programs

T Fulton

 

10:00

Break

 

 

10:30

Molecular Cloning: Library construction

S Mitchell

 

12:00

Lunch

 

 

01:30

Ligation & Transformation of E. Coli

Team

 

03:00

Break

 

 

03:30

Plating?

PAGE?

 

 

 

 

 

 

8 July

Tuesday

09:00

Proteomics & other ÔomicsÕ: whatÕs on the horizon

T Fulton

 

10:00

Break

 

 

10:30

Marker-assisted selection: complications of polyploidy

R Koebner

 

12:00

Lunch

 

 

01:30

Strategic banana and plantain

improvement project at IITA: status and way forward

Irie Vroh Bi (IITA)

 

03:00

Break

 

 

03:30

Manuscript writing, Poster Design

R Koebner

 

 

 

 

9 July

09:00

Team Presentations

 

Wed

10:30

Break

 

 

11:00

Team Presentations, contd.

 

 

12:00

Lunch

 

 

01:30

Team Presentations

Discussion of use of markers, Question & Answers

 

 

03:00

Break

 

 

03:30

Seminar: Identification of a MADS-box gene family and phylogenetic analysis of the mikc subgroup in cowpea

Joseph Opoku

 

 

 

 

10 July

09:00

Seminar??

??? Walter Alhassan?

Thurs

10:30

Break

 

 

11:00

Course evaluations

 

 

12:00

Lunch

 

 

01:30

 

 

 

 

Wrap-up, questions

 

 

 

 

 

 

 

Group Dinner